Definitions

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  • noun Plural form of cochaperone.

Etymologies

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Examples

  • Furthermore, HSF1A-B did not interact with Hsp90 or the cochaperones Cdc37, Hop, p23, or Hsp70, nor HSF1 itself in pull-down experiments with mammalian cell extracts (unpublished data).

    PLoS Biology: New Articles Daniel W. Neef et al. 2010

  • H, Mollapour M, Panaretou B, Siligardi G, et al. (2003) Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast.

    PLoS Biology: New Articles Daniel W. Neef et al. 2010

  • Previous studies suggest that Hsp90 and additional cochaperones exist in a heteroprotein complex that, in addition to their central role in cellular signaling, function to repress HSF1 in the absence of stress.

    PLoS Biology: New Articles Daniel W. Neef et al. 2010

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