from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. An antibiotic produced by the bacterium Bacillus polymyxa or B. colistinus that is effective against a wide range of gram-negative bacteria and is used especially in the treatment of infections of the gastrointestinal tract.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A polymixin antibiotic effective against a range of gram-negative bacteria


from The American Heritage® Dictionary of the English Language, 4th Edition

From New Latin Colistīnus, species name, from coli-.


  • "Indian supergene" NDM-1 - there has been one hopeful thread: All of the organisms have remained susceptible to one very old, little-used drug called colistin.

    Wired Top Stories

  • CALLER: Your program recommended the product colistin.

    CNN Transcript Mar 5, 2003

  • Many doctors have even tried colistin, a 50-year-old drug so potent that it can damage kidneys. -- Top News

  • We currently market colistin in the U.K. and Ireland.

    Forest Laboratories Q3 2011 Earnings Call Transcript - Seeking Alpha

  • With the continued use of colistin for treatment of infection with various multidrug-resistant Gram-negative pathogens, it is likely that we will see an increasing number of instances of both de novo emergence of resistance and nosocomial spread.

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  • She never had CRKP, and never received colistin - but in the middle of May, she was discovered to have a urinary tract infection that was colistin-resistant.

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  • He entered the transplant intensive care unit at the end of February, was diagnosed with CRKP in early April, got colistin, and was discovered to have colistin-resistant

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  • After she had been there two months, she was also diagnosed with CRKP, and also began receiving colistin.

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  • It was susceptible to both tigecycline and colistin.

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  • Klebsiella or CRKP, an increasingly common drug-resistant organism subject of my Scientific American piece last April for which the drugs colistin and tigecycline are the only remaining treatments.

    Wired Top Stories


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