Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. An anomaly of the eye, usually a developmental defect, that often results in some loss of vision.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An abnormal hole present from birth in one of the structures of the eye, such as the lens, eyelid, or retina.

from the GNU version of the Collaborative International Dictionary of English

  • n. A defect or malformation; esp., a fissure of the iris supposed to be a persistent embryonic cleft.

from The Century Dictionary and Cyclopedia

  • n. In medicine: The part taken away in mutilation; a mutilation; a defect.
  • n. A defect in the iris, choroid, retina, optic nerve, or lens, due to incomplete or perverted closing of the choroidal fissure: also used for other fissures in the eye or its lids.

Etymologies

New Latin colobōma, from Greek kolobōma, part removed in mutilation, from koloboun, to mutilate, from kolobos, maimed.
(American Heritage® Dictionary of the English Language, Fourth Edition)

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