from The American Heritage® Dictionary of the English Language, 4th Edition
- n. An anomaly of the eye, usually a developmental defect, that often results in some loss of vision.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. An abnormal hole present from birth in one of the structures of the eye, such as the lens, eyelid, or retina.
from the GNU version of the Collaborative International Dictionary of English
- n. A defect or malformation; esp., a fissure of the iris supposed to be a persistent embryonic cleft.
from The Century Dictionary and Cyclopedia
- n. In medicine: The part taken away in mutilation; a mutilation; a defect.
- n. A defect in the iris, choroid, retina, optic nerve, or lens, due to incomplete or perverted closing of the choroidal fissure: also used for other fissures in the eye or its lids.
Sometimes the choroidal fissure persists, and when this occurs the choroid and iris in the region of the fissure remain undeveloped, giving rise to the condition known as coloboma of the choroid or iris.
Again, the iris may be the seat of a malformation, termed coloboma, which consists in a deficiency or cleft, clearly due in a great number of cases to an arrest in development.
Loper, because of a hereditary disease, coloboma, was born blind in her right eye.
Thomas Henderson maintains that the results of iridectomy are beneficial because the raw edges of the coloboma, which do not cicatrize, permit access of the aqueous to the iris veins, and that myotics, inasmuch as they contract the pupil, open the iris crypts and therefore act, less efficiently, perhaps, but act none the less like an iridectomy.
Posey 6.178 had a case of coloboma in the macular region in a patient who had a supernumerary tooth.
In three generations twelve members of one family had either coloboma iridis or irideremia.
Posey had a case of coloboma in the macular region in a patient who had a supernumerary tooth.
Apparently if one's pupil is irregularly shaped it could be due to simply just a genetic variation (which is normal) or more serious things such as iritis, multiple sclerosis, coloboma, previous cataract surgery, and/or neurosyphilis.
6.177 In three generations twelve members of one family had either coloboma iridis or irideremia.
"hey, my son is 7yrs old and he has bilateral coloboma. i first noticed when he was about 3 weeks ..."