from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. The conversion of squamous epithelial cells into a keratinized horny material, such as hair, nails, or feathers.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Conversion into, or formation of, horn; a becoming like horn.

from the GNU version of the Collaborative International Dictionary of English

  • n. Conversion into, or formation of, horn; a becoming like horn.

from The Century Dictionary and Cyclopedia

  • n. Production of horn; conversion into horn; the process or result of becoming horny or corneous.
  • n. The growing of horns.


Latin cornū, horn; see ker-1 in Indo-European roots + -fication.
(American Heritage® Dictionary of the English Language, Fourth Edition)


  • By comparison, the normal mice formed a thick, robust outer skin barrier, with more tightly linked, toughened cells (a process known as cornification). - latest science and technology news stories

  • The tongue is studded over with white patches, which result from overgrowth and cornification of the surface epithelium, whereby it becomes thickened and raised above the surface, and at the same time there is small-celled infiltration of the submucous tissue.

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  • OF THE HORNY SCALE, and became an organ of touch subsequently by the cornification of the hairs; many hairs are still sensory organs

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  • The best way would be to have the bitch examined and include palpation of the uterine stump, vaginal smears to monitor cornification of the vagina, changes in the vulva and general health of the bitch.


  • Mischke D, Korge B, Marenholz I, Volz A, Ziegler A (1996) Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ( "epidermal differentiation complex") on human chromosome 1q21.

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  • It has been discovered that common loss-of-function mutations within the FLG gene cause ichthyosis vulgaris, one of the most common heritable disorders of cornification, and represent major risk factors for atopic dermatitis (AD) and secondary allergic diseases

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  • Bern H. A.: Tissue changes in mice with persistent vaginal cornification induced by early postnatal treatment with estrogen.

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  • Davenport says it "is especially apt to be found in families in which consanguineous marriages occur and this fact, together with the pedigrees [which he studied], suggests that it is due to the absence of some factor that controls the process of cornification of the skin.

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