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Examples
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An interdependence of enterocyte differentiation along the crypt-villus axis and fls485 chaperone activity might be possible.
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Immunhistochemistry demonstrated fls485 as a cytosolic protein with a slightly increasing expression gradient along the crypt-villus axis which was impaired in celiac disease Marsh IIIa-c.
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Maturation of enterocytes along small intestinal crypt-villus axis is associated with significant changes in gene expression profiles. fls485 coding a putative chaperone protein has been recently suggested as a gene involved in this process.
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The β-catenin/T cell factor (TCF) signal transduction pathway plays a critical role in the regulation of proliferation and differentiation of the intestinal epithelial cells during the regeneration and maturation process along the crypt-villus axis
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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Crypt depth was independently and objectively analyzed and quantitated in a blind fashion from coded digital photographs of crypts from H&E stained slides using ImageJ 1.37 software to measure the height in pixels from the bottom of the crypt to the crypt-villus junction.
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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This resulted in an increase in the overall size of the crypts, as determined by measuring crypt depth from the base of the crypt to the crypt-villus junction (
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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