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- n. anaphase-promoting complex
Sorry, no etymologies found.
The metaphase-anaphase transition is orchestrated through proteolysis of numerous proteins by a ubiquitin protein ligase called the anaphase-promoting complex or cyclosome (APC/C).
Moshe, Y., and Hershko, A. (2007) Inhibitory factors associated with the anaphase-promoting complex / cyclosome in mitotic checkpoint.
V., and Hershko, A. (1995) The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis.
This resulted in the identification of two ubiquitin-protein ligase complexes: the cyclosome, now also called anaphase-promoting complex or APC / C, involved in the degradation of mitotic cyclins and some other cell cycle regulatory proteins in exit from mitosis
Here, we report that Atf1 has a distinct role in regulating the anaphase-promoting complex/cyclosome
Stewart S, Fang G (2005) Anaphase-promoting complex / cyclosome controls the stability of TPX2 during mitotic exit.
The anaphase-promoting complex / cyclosome (APC / C) activator genes