from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An antineoplastic drug used in chemotherapy.


Sorry, no etymologies found.


  • Among patients who got Yervoy combined with the current standard of care, a cell-killing drug called dacarbazine, 21% were alive after three years, compared with 12% for those getting dacarbazine alone.

    Bristol-Myers pitches its cancer medicine pipeline

  • The toxicity associated with FDA-approved treatments such as dacarbazine or interleukin-2 is often significant, resulting in serious or life-threatening side effects in many of the patients treated.


  • Roche said participants in the study who received RG7204 lived longer and also lived longer without their disease getting worse, compared with participants who received dacarbazine, the current standard of care.

    Roche Skin-Cancer Drug Shows Promise

  • First-line treatment for advanced cases includes the drug dacarbazine, but there are no approved second-line treatments.

    Bristol Drug Extends Survival In Skin-Cancer Trial

  • The company also is testing whether adding ipilimumab to the dacarbazine is any better than dacarbazine alone in untreated melanoma.

    Bristol Drug Extends Survival In Skin-Cancer Trial

  • Almost half of patients taking Yervoy with the chemotherapy dacarbazine were alive after a year, compared with one-third given the chemotherapy alone. -- Top News

  • Researchers also reported that combining the standard chemotherapy drug dacarbazine with a new compound that simulates the immune system known as ipilimumab, or Yervoy, improved the chances that advanced melanoma patients would survive.

    The Washington Post: National, World & D.C. Area News and Headlines - The Washington Post

  • After a median three months of treatment, vemurafenib patients also had a 74 percent reduction in the risk of cancer progression compared to dacarbazine.

    Reuters: Top News

  • "We don't know what dacarbazine did to the ipilimumab, but we do know even in the presence of dacarbazine, ipilimumab still produced a durable response and extended survival."

    Reuters: Top News

  • "What was interesting about this study was not only was it the second one to show a benefit," but that the improvement "took place even in the presence of dacarbazine chemotherapy," Dr. Jedd Wolchok of Memorial Sloan-Kettering Cancer Center in New York, who presented the study at the meeting, said in a telephone interview.

    Reuters: Top News


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