Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun An
antineoplastic drug used inchemotherapy .
Etymologies
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Examples
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Among patients who got Yervoy combined with the current standard of care, a cell-killing drug called dacarbazine, 21% were alive after three years, compared with 12% for those getting dacarbazine alone.
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Among patients who got Yervoy combined with the current standard of care, a cell-killing drug called dacarbazine, 21% were alive after three years, compared with 12% for those getting dacarbazine alone.
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The toxicity associated with FDA-approved treatments such as dacarbazine or interleukin-2 is often significant, resulting in serious or life-threatening side effects in many of the patients treated.
News 2010
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Among patients who got Yervoy combined with the current standard of care, a cell-killing drug called dacarbazine, 21% were alive after three years, compared with 12% for those getting dacarbazine alone.
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Among patients who got Yervoy combined with the current standard of care, a cell-killing drug called dacarbazine, 21% were alive after three years, compared with 12% for those getting dacarbazine alone.
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Roche said participants in the study who received RG7204 lived longer and also lived longer without their disease getting worse, compared with participants who received dacarbazine, the current standard of care.
Roche Skin-Cancer Drug Shows Promise Goran Mijuk 2011
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The company also is testing whether adding ipilimumab to the dacarbazine is any better than dacarbazine alone in untreated melanoma.
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First-line treatment for advanced cases includes the drug dacarbazine, but there are no approved second-line treatments.
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Almost half of patients taking Yervoy with the chemotherapy dacarbazine were alive after a year, compared with one-third given the chemotherapy alone.
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Researchers also reported that combining the standard chemotherapy drug dacarbazine with a new compound that simulates the immune system known as ipilimumab, or Yervoy, improved the chances that advanced melanoma patients would survive.
The Washington Post: National, World & D.C. Area News and Headlines - The Washington Post Rob Stein 2011
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