Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A particular
anthracycline drug used inchemotherapy .
Etymologies
Sorry, no etymologies found.
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Examples
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When a 12-year-old boy from Illinois with ALL arrived at St. Jude in 2001, Pui administered everything but the kitchen sink: the drugs prednisone, vincristine, daunorubicin, and asparaginase, followed by cyclophosphamide, cytarabine, and mercaptopurine.
Curing Cancer 2010
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The same regimen is being compared with daunorubicin plus cytarabine in a pivotal randomised phase III trial, ACCEDE, which is expected to report data in late 2010 or early 2011.
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The 627 patient-trial, called SWOG S0106, began in 2004 but was stopped early after an interim analysis revealed that Mylotarg in combination with standard chemotherapy (daunorubicin and cytosine arabinoside) did not demonstrate improved survival compared with chemotherapy alone in patients with previously-untreated AML.
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UKALL VIII examined the role of daunorubicin in induction chemotherapy, and UKALL X examined the role of post-induction intensification.
Naturejobs - All Jobs C Mitchell 2010
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The same regimen is being compared with daunorubicin plus cytarabine in a pivotal randomised phase III trial, ACCEDE, which is expected to report data in late 2010 or early 2011.
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The trial compares AS1413-based treatment with standard current treatment based on the classical TopoII inhibitor daunorubicin.
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The standard treatment for AML is high-dose daunorubicin plus cytarabine.
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* #3665 The novel DNA intercalator amonafide (AS1413) disrupts the cell cycle by mechanisms distinct from topo II inhibitors daunorubicin and etoposide (Senderovich et al.)
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* #3665 The novel DNA intercalator amonafide (AS1413) disrupts the cell cycle by mechanisms distinct from topo II inhibitors daunorubicin and etoposide (Senderovich et al.)
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The trial compares AS1413-based treatment with standard current treatment based on the classical TopoII inhibitor daunorubicin.
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