Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun The process of losing granules.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biology The loss of secretory granules in certain cells

Etymologies

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Examples

  • For example, when a stray pollen grain finds its way into a hay fever sufferer's airways, their mast cells overreact, spilling their contents in a process known as 'degranulation'.

    unknown title 2009

  • Inhibition of human basophil degranulation by successive histamine dilutions: results of a European multi-centre trial.

    Dana Ullman: Disinformation on Homeopathy: Two Leading Sources Dana Ullman 2011

  • "Human basophil degranulation triggered by very dilute antiserum against IgE".

    Dana Ullman: Nobel Prize Winner Takes Homeopathy Seriously Dana Ullman 2011

  • "Human basophil degranulation triggered by very dilute antiserum against IgE".

    Dana Ullman: Nobel Prize Winner Takes Homeopathy Seriously Dana Ullman 2011

  • Olopatadine (Patanol), nedocromil (Alocril), and ketotifen (Zaditor), are used in order to prevent the membrane changes and the decrease in degranulation of mast cells, having as a result the increase of the resistance against the exposure to the allergen.

    Allergic Conjunctivitis Treatment 2008

  • When an allergen binds between two IgE antibodies, it induces degranulation of a mast cell/basophil, which leads to the rapid release of histamine and the more gradual release of other mediators such as leukotrienes and cytokines.

    The Different Types of Dairy Allergy Steve Carper 2006

  • When an allergen binds between two IgE antibodies, it induces degranulation of a mast cell/basophil, which leads to the rapid release of histamine and the more gradual release of other mediators such as leukotrienes and cytokines.

    Archive 2006-03-01 Steve Carper 2006

  • Human basophil degranulation triggered by very dilute antiserum against IgE.

    The Best Alternative Medicine Dr. Kenneth R. Pelletier 2000

  • Human basophil degranulation triggered by very dilute antiserum against IgE.

    The Best Alternative Medicine Dr. Kenneth R. Pelletier 2000

  • H2 phenotype, leading to Ig subtype switching and IgE synthesis, mast cell degranulation, eosinophilia, mucus metaplasia and airway hyperresponsiveness.

    PLoS ONE Alerts: New Articles Neelkamal Chaudhary et al. 2010

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