demethylated

The elimination of caffein has also been studied by Salant and Reiger [272], who found that larger amounts of caffein are demethylated in carnivora than in herbivora, and resistance to caffein is inversely as demethylation, caffein being much more toxic in the former class.

All About Coffee 1909

Genome-wide analysis showed that a significant portion of epidermal differentiation gene promoters were methylated in self-renewing conditions but were subsequently demethylated during differentiation.

Naturejobs - All Jobs George L. Sen 2010

We also show that DOT1L, the major H3K79 histone methyltransferase, is no longer recruited to the promoters that are demethylated after

Naturejobs - All Jobs F V Jacinto 2009

To selectively amplify demethylated promoter regions in genes of interest, probe and primers were designed using data from bisulfite sequencing of primary tumors which are complementary only to bisulfite-converted sequences known to be demethylated in tumor.

PLoS ONE Alerts: New Articles Ian M. Smith et al. 2009

We also show that DOT1L, the major H3K79 histone methyltransferase, is no longer recruited to the promoters that are demethylated after

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H19 gene locus, which is demethylated in oocytes after establishment of the maternal imprint, is hypomethylated in PGC-like cells compared to undifferentiated skin-derived stem cells, suggesting that the putative germ cell population undergoes imprint erasure.

Elites TV 2009

(HNSCC) and pharmacologically demethylated cell lines to identify aberrantly demethylated and expressed candidate proto-oncogenes and cancer testes antigens in HNSCC.

PLoS ONE Alerts: New Articles Ian M. Smith et al. 2009

We were also able to define these groups according to promoter homology, implicating the participation of promoter-specific binding activity in the coordinated expression of each of these groups and suggesting the existence of additional common transcriptional activators that recognize the specific demethylated promoter sequences of these genes.

PLoS ONE Alerts: New Articles Ian M. Smith et al. 2009

Expression patterns correlate with promoter homology for promoter demethylated target genes

PLoS ONE Alerts: New Articles Ian M. Smith et al. 2009

H19 and the MAGE family members showed significant correlation in this expression and demethylated promoter status in HNSCC and NSCLC.

PLoS ONE Alerts: New Articles Ian M. Smith et al. 2009