deoxyribozyme

Scientists at The Scripps Research Institute have successfully converted an RNA enzyme (ribozyme) into a DNA enzyme (deoxyribozyme) through a process of accelerated in vitro evolution.

Dark matter, coal-fueled jets.... 2006

Extant biology is due to the co-option of DNAptazyme and deoxyribozyme functionalities by RNA and protein to the specific functionalities to which they now seem best suited (short-term memory, amplification, reconfiguration, reutilization, graceful degradation, etc.).

A Minimal Genome 2006

The result was a deoxyribozyme with about the same level of catalytic activity as the original ribozyme.

Good Math, Bad Math, and David Berlinkski - The Panda's Thumb 2006

The catalytic function of these early enzymes might have been transferred to a corresponding RNA enzyme following the acquisition of a few critical mutations, the study said, just as the evolutionary change of a ribozyme to a deoxyribozyme with the same or similar catalytic functions might also have occurred through random mutation and selection.

Good Math, Bad Math, and David Berlinkski - The Panda's Thumb 2006

For the study, an RNA ribozyme was converted to a corresponding deoxyribozyme through in vitro evolution.

Good Math, Bad Math, and David Berlinkski - The Panda's Thumb 2006

“The use of in vitro evolution provides the means to convert a ribozyme to a corresponding deoxyribozyme rapidly,” Joyce said.

Good Math, Bad Math, and David Berlinkski - The Panda's Thumb 2006