dihydropyridine love

dihydropyridine

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A molecule based upon pyridine, the parent of a class of molecules that have been semi-saturated with two substituents replacing one double bond.

Etymologies

di- +‎ hydropyridine (Wiktionary)

Examples

  • [3H] dihydropyridine binding in A7r5 vascular smooth muscle cells.

    PLoS ONE Alerts: New Articles

  • Recent studies also find that in cultured differentiated neonatal cardiomyocytes, the dihydropyridine receptor

    PLoS Biology: New Articles

  • Dr. Beate Ritz, professor of epidemiology at the UCLA School of Public Health, in collaboration with researchers from the Danish Cancer Society, found that a specific sub-class of dihydropyridine cardiovascular medications was associated with a 26 to 30 percent decrease in the risk of Parkinson's.

    Medindia Health News

  • We found that of all the hypertension medications taken by our study subjects, only the subset of dihydropyridine class drugs that cross into the brain, where they might be able to act on the calcium channels of neurons, provided a protective effect.

    UCLA Newsroom: UCLA Newsroom

  • In the first large-scale population-based study of its kind, Dr. Beate Ritz, professor of epidemiology at the UCLA School of Public Health, in collaboration with researchers from the Danish Cancer Society, found that a specific sub-class of dihydropyridine cardiovascular medications was associated with a 26 to 30 percent decrease in the risk of Parkinson's.

    UCLA Newsroom: UCLA Newsroom

  • In the heart, the dihydropyridine class of drugs acts on a specific type of channel known as the L-type.

    UCLA Newsroom: UCLA Newsroom

  • Within the dihydropyridine class is a sub-class of medications that can cross the blood-brain barrier, giving them the potential to act on neurons in the brain.

    UCLA Newsroom: UCLA Newsroom

  • By separately evaluating different classes of a variety of drugs prescribed for hypertension, researchers found that only calcium channel blockers of the dihydropyridine sub-class that cross the blood-brain barrier were associated with a significant decrease in the risk of developing Parkinson's.

    UCLA Newsroom: UCLA Newsroom

  • When exposed to NO, in the presence of oxygen, the dihydropyridine ring is oxidised - to a planar pyridine ring.

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  • In the case of the NO sensor, the team have designed a precursor based on a non-planar dihydropyridine.

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