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Examples
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Last week, the company said it would give its medicine bottles a new cap, called a flow restrictor or dose-limiting cap, that allows parents to insert a syringe to draw out the correct dose.
J&J, Others to Revamp Pain Drug Jonathan D. Rockoff 2011
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He detailed steps J&J was taking, including the renovation of a manufacturing plant outside Philadelphia and a plan for "dose-limiting" packaging for medicines for children and infants.
J&J Shareholders Approve Executive-Compensation Policy Peter Loftus 2011
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“The dose-limiting barrier,” Bezwoda announced audaciously in 1992, had been “overcome”—instantly rocketing himself and his clinic into stratospheric fame.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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“The dose-limiting barrier,” Bezwoda announced audaciously in 1992, had been “overcome”—instantly rocketing himself and his clinic into stratospheric fame.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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“The dose-limiting barrier,” Bezwoda announced audaciously in 1992, had been “overcome”—instantly rocketing himself and his clinic into stratospheric fame.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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However, no treatment approach is curative and all treatments eventually fail, either for reasons related to dose-limiting adverse events, non-compliance, the evolution of resistance or combination of all these.
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Most of these non dose-limiting AEs were mild, such as mild dizziness and nausea.
unknown title 2011
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We believe that the dose-limiting effects we began to see in the Phase 1 trial may not have been related to the RONDEL system, but rather to the naked siRNA inside.
unknown title 2011
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Dose-related, easily-monitored and reversible neutropenia was the only dose-limiting event.
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NKTR-181 was well tolerated at all doses, with very few reports of adverse events (AEs) until the highest dose level tested (500 mg), when transient non dose-limiting AEs characteristic of an active opioid agonist were reported.
unknown title 2011
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