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down-regulation

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun Alternative spelling of downregulation.

Etymologies

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Examples

  • Perhaps the lack of response in moss and lichens reflects their adaptation to the currently high levels of CO2 that they experience close to the ground surface [106] via the process of down-regulation.

    Phenotypic responses of arctic species to changes in climate and ultraviolet-B radiation 2009

  • The first experiment that manipulated CO2 in the Arctic concluded that elevated CO2 concentrations had no long-term effects because photosynthetic acclimation (i.e., down-regulation, the physiological adjustment of photosynthetic rate so that no differences are found between plants grown at ambient and elevated CO2 levels) in cottongrass ( '' Eriophorum vaginatum '') was apparent within three weeks and biomass did not increase.

    Phenotypic responses of arctic species to changes in climate and ultraviolet-B radiation 2009

  • When we quiet the mind, contemplate, and conceive the details of what we desire, this affects the development of neural pathways that promote the down-regulation of the sympathetic nervous system, (read this as 'stress central'), and promotes relaxation, harmony, well-being.

    Dr. Cara Barker: The Art of Rewriting The Holidays 2009

  • In any case, the goal is to find a target where up- or down-regulation might plausibly be therapeutic, and then to develop a high-throughput assay for that up- or down-regulation.

    How drugs are made: part I Silas 2008

  • In any case, the goal is to find a target where up- or down-regulation might plausibly be therapeutic, and then to develop a high-throughput assay for that up- or down-regulation.

    Archive 2008-07-01 Yttrai 2008

  • Vpu-mediated CD4 down-regulation and degradation is conserved among highly divergent SIVcpz strains

    ERV & HIV versus Behe. Behe loses. - The Panda's Thumb 2007

  • As such, these cells have the potential to move the regenerative medical field beyond the classic paracrine mechanisms neoangiogenesis and down-regulation of inflammation toward tissue and bone repair and regeneration.

    unknown title 2011

  • We also identified down-regulation of catalase, which has important antioxidant functions.

    PLoS ONE Alerts: New Articles Franco Folli et al. 2010

  • Effects of trehalose injection on expressions of key genes in the chitin biosynthesis pathway In addition to the down-regulation of trehalase expression, an examination of an indirect up-regulation of trehalases by the injection of trehalose was conducted.

    PLoS ONE Alerts: New Articles Jie Chen et al. 2010

  • Unlike other RNA therapeutic approaches, AVI's antisense technology has been used to directly target both messenger RNA (mRNA) and its precursor (pre-mRNA), allowing for both up and down-regulation of targeted genes and proteins.

    Marketwire - Breaking News Releases 2010

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