from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Plural form of duplicon.
Sorry, no etymologies found.
The largest pair of duplicons, 108 kb in length located on the left arm of Chromosome V, was further characterized.
We detected 3,484 duplicated segments -- duplicons -- ranging in size from 234 bp to 108 kb.
Using the physical map, we observed that, similar to MIB duplicons, highly divergent Mamu-B genes can be present on the same haplotype.
In silico research pinpointed 12 MIB copies (duplicons), most of which are associated with expressed B-genes that cluster in a separate clade in the phylogenetic tree.
Phylogenetic analyses highlight a strong transpecific sharing of MIB duplicons.
Furthermore, our qPCR analysis led us to presume CHEK2 copy number variation in human, and molecular diagnostics of the cancer susceptibility gene CHEK2 inside the duplicated region might be hampered by the individual-specific set of duplicons.