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from Wiktionary, Creative Commons Attribution/Share-Alike License

  • v. To cause a dysfunctional level of an activity or chemical in an organism by disrupting normal function of a regulatory mechanism.


dys- +‎ regulate (Wiktionary)


  • Loud neurochemical "GOTTA GET IT!" signals arising from fantasy can dysregulate your brain's reward circuitry-and skew your priorities.

    Psychology Today

  • Third, expression of expanded CUG repeat sequences have been shown to dysregulate RNA splicing due to the inactivation of the alternative splice regulator, MBNL1, by mechanisms that have yet to be fully understood

    PLoS ONE Alerts: New Articles

  • Prenatal smoke exposure-induced low MAO-A activity in fetal life may dysregulate brain neurotransmission, creating a potential vulnerability to develop behavioral disorders later in life.


  • Animal studies support the concept that in humans prenatal exposure to continuous high doses of beta 2 adrenergic agonists can permanently dysregulate signaling from the beta 2 adrenergic receptor.

    EurekAlert! - Breaking News


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