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- n. Plural form of echinocandin.
Sorry, no etymologies found.
After less than eight years on the market, clinical use of the new front line drugs for treating systemic fungal infections, known as echinocandins, is already being threatened by the appearance of clinical isolates with increased resistance to their antifungal activity.
Inhibiting the Rgc proteins alone does not kill the fungal cells but makes them more sensitive to the effect of echinocandins.
Importantly, the echinocandins provide novel and powerful chemical tools to probe the still poorly understood bi-phasic life cycle of this genus of fungal pathogens.
, despite the availability of potent drugs such as amphotericin B, azole derivatives or echinocandins