from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. An allosteric effector of haemoglobin that increases its oxygen-carrying capacity and can be used to increase the efficacy of certain chemotherapy drugs.
Sorry, no etymologies found.
Researchers have been hunting for ways to improve radiation therapy, and drugs such as efaproxiral seemed promising, according to Ramesh Rengan, M.D.,
BOSTON, Sept. 24 -- An investigational radiation sensitizer, efaproxiral (Efaproxyn), had no significant benefit for women whose breast cancers had spread to the brain, a researcher said here.
They were treated with three Gray of whole brain radiation daily for 10 days, with or without efaproxiral delivered by a central venous access device.
The finding contrasts with an earlier study that had seemed to show a benefit for women who got efaproxiral combined with whole-brain radiation, according to John Suh, M.D., of the Cleveland Clinic.
At three months, confirmed complete response and partial responses were seen in 31\% of efaproxiral patients and in 27\% of those in the control arm, but the difference was not significant.
Median survival time was 8.5 months in the efaproxiral arm and 7.5 months in the control arm, which was not significant (