from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biology A
cycleof cell replicationinvolving endoduplication
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Once a cell has decided to endoreduplicate, it continues to endocycle and cannot resume mitotic divisions
CDH1, FZR, and CCS52 are known to promote endocycle onset in human,
The timing of endocycle onset is crucial for correct development, because polyploidization is linked with cessation of cell division and initiation of terminal differentiation.
The endocycle represents an alternative cell cycle that is activated in various developmental processes, including placental formation,
CCS52A2 transcription, affecting the timing of endocycle onset.
CCS52A2 expression drove cells into the endocycle prematurely.
Dynamic simulation illustrated that E2Fe / DEL1 accounted for the onset of the endocycle by regulating the temporal expression of