Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun chemistry (biochemistry) Any heterocycle containing a peroxide -O-O- residue in the ring; found especially in certain intermediates in prostaglandin biosynthesis.

Etymologies

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Examples

  • It does this by irreversibly blocking the enzyme cyclooxygenase (COX), which catalyzes the conversion of arachidonic acid to endoperoxide compounds.

    Aspirin: effects, poisoning 2010

  • Prostaglandin endoperoxide H synthases (PGHSs) 1 and 2, also known as cyclooxygenases (COXs), catalyze the oxygenation of arachidonic acid (AA) in the committed step in prostaglandin

    Journal of Biological Chemistry current issue 2009

  • Variants of two genes were associated with increased risk of kidney cancer: nitric oxide synthase 2A (NOS2A), which increases levels of nitric oxide, a chemical that promotes free radical damage to cells; and prostaglandin-endoperoxide 2 (PTGS2), which produces prostaglandins, compounds that cause inflammation.

    Medlogs - Recent stories 2008

  • The uterine infection caused a massive (~90-fold) upregulation of the prostaglandin-endoperoxide synthase 2/cyclooxygenase-2 gene (PTGS2) (

    PLoS ONE Alerts: New Articles Ragnvi Hagman et al. 2009

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