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- noun Plural form of
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This has led to the discovery of endoperoxides, thromboxanes and the leukotrienes, and my group has mainly been involved in studying the chemistry, biochemistry and biology of these compounds and their role in biological control system.
Samuelsson's discoveries of the endoperoxides, thromboxanes and leukotrienes were crucial for our present understanding of the biological significance of this system.
In one of them the cyclic endoperoxides constitute an important branching point from which the stable prostaglandins as well as the more unstable thromboxanes and prostacyclin are formed.
The metabolites of the endoperoxides (the stable prostaglandins, the thromboxanes and prostacyclin) haye been called defense hormones.
As illustrated in the figure steroids inhibit the formation of both endoperoxides and leukotrienes from arachidonic acid, while aspirin only blocks the formation of endoperoxides.