Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun medicine any hereditary characteristic that is normally associated with some condition but is not a direct symptom of that condition.

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

endo- +‎ phenotype

Examples

  • This comes at a time when psychiatry is looking beyond the current diagnostic manuals as the sole definition of mental disorder, and considering the concept of the 'endophenotype' - measurable aspects of biology thought to be the key underlying components that increase risk for mental disorder.

    Mind Hacks: October 2005 Archives

  • This comes at a time when psychiatry is looking beyond the current diagnostic manuals as the sole definition of mental disorder, and considering the concept of the 'endophenotype' - measurable aspects of biology thought to be the key underlying components that increase risk for mental disorder.

    Mind Hacks: Brain scans, mental illness and false promises

  • Link to academic paper on the 'endophenotype' concept.

    Mind Hacks: October 2005 Archives

  • Link to academic paper on the 'endophenotype' concept.

    Mind Hacks: Brain scans, mental illness and false promises

  • Yes, the genetics of it are complicated, it's an area of interest viz work for me, but I think the point I was trying to make was more along the lines of how genetics interacts with human culture and history and nurture (the latter leading to the 'endophenotype') to produce selection that isn't the straightforward natural selection process in the wild - of survival of the fitest in the wild.

    Articles

  • Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism.

    Autism Research: Breakthrough Discovery on the Causes of Autism

  • Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism.

    Mark Hyman, MD: Autism Research: Breakthrough Discovery on the Causes of Autism

  • Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism.

    The Full Feed from HuffingtonPost.com

  • Chen P, Jou YS, Fann CS, Chen JW, Chung CM, et al. (2009) Lipoprotein lipase variants associated with an endophenotype of hypertension: hypertension combined with elevated triglycerides.

    PLoS ONE Alerts: New Articles

  • Watanabe A, Toyota T, Owada Y, Hayashi T, Iwayama Y, et al. (2007) Fabp7 maps to a quantitative trait locus for a schizophrenia endophenotype.

    PLoS ONE Alerts: New Articles

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