endophenotypes love


from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of endophenotype.


Sorry, no etymologies found.


  • Psychiatry is increasingly using this approach to identify the 'endophenotypes' of disorders, in an attempt to get away from an understanding of mental illness based largely on self-reported symptoms.

    Mind Hacks: Neuroimaging genetics

  • Frequency distribution of P values showed a greater proportion of significant associations with the latent LVDF trait than for the measured endophenotypes, suggesting that analyses of the latent trait improved detection of the genetic underpinnings of LVDF.

    BioMed Central - Latest articles

  • By linear regression analysis, 7 SNPs (4 in PPARA, 2 in PPARGC1A, 1 in PPARG) were significantly associated with the latent LVDF trait, whereas a range of 0-4 SNPs were associated with each of the 14 measured echocardiography-derived endophenotypes.

    BioMed Central - Latest articles

  • Independent component analysis was applied to extract latent LVDF traits from 14 measured echocardiography-derived endophenotypes of LVDF in 403 Caucasians.

    BioMed Central - Latest articles

  • We aimed to study associations of common RGS4 variants with prefrontal dependent cognitive performance and schizotypy endophenotypes at the population level.

    BioMed Central - Latest articles

  • There was no clear evidence for any association of the RGS4 variants with cognitive endophenotypes, except for an isolated effect of SNP18 on antisaccade error rate (p = 0.028 for allele-load model).

    BioMed Central - Latest articles

  • The identification and investigation of clinical endophenotypes may be one solution, but represents a considerable challenge in human subjects.

    BioMed Central - Latest articles


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