Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry An accessory protein that has several functions associated with cell membranes

Etymologies

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Examples

  • They identified that parkin binds to a protein called endophilin-A, a protein discovered at The Neuro in 1997 by Dr. Peter McPherson, a co-investigator on the current study.

    PhysOrg.com - latest science and technology news stories 2010

  • They identified that parkin binds to a protein called endophilin-A, a protein discovered at The Neuro in 1997 by Dr. Peter McPherson, a co-investigator on the current study.

    PhysOrg.com - latest science and technology news stories 2010

  • They identified that parkin binds to a protein called endophilin-A, a protein discovered at The Neuro in 1997 by Dr. Peter McPherson, a co-investigator on the current study.

    PhysOrg.com - latest science and technology news stories 2010

  • The binding protein, endophilin-A plays an important role in regulating synaptic vesicle endocytosis, that is the formation, as well as recycling of synaptic vesicles.

    PhysOrg.com - latest science and technology news stories 2010

  • Thus, by linking parkin to endophilin-A, a protein at the heart of synaptic vesicle endocytosis and recycling, our findings provide a molecular link between recessive Parkinson's genes and defects in synaptic transmission.

    PhysOrg.com - latest science and technology news stories 2010

  • Chen Y, Deng L, Maeno-Hikichi Y, Lai M, Chang S, et al. (2003) Formation of an endophilin-Ca2+ channel complex is critical for clathrin-mediated synaptic vesicle endocytosis.

    PLoS Biology: New Articles Ting-Ting Hong et al. 2010

  • It appears that BIN1 recruitment of Cav1. 2 involves a domain distinct from the one that induces membrane curvature, as suggested by endophilin binding to Cav1. 2 in its non-BAR coiled-coil region

    PLoS Biology: New Articles Ting-Ting Hong et al. 2010

  • Thus, by linking parkin to endophilin-A, a protein at the heart of synaptic vesicle endocytosis and recycling, our findings provide a molecular link between recessive Parkinson's genes and defects in synaptic transmission.

    PhysOrg.com - latest science and technology news stories 2010

  • Supporting evidence for this Cav1. 2 localization hypothesis is that another BAR domain containing protein, endophilin, has been shown to complex with Cav1. 2 at the plasma membrane

    PLoS Biology: New Articles Ting-Ting Hong et al. 2010

  • Thus, by linking parkin to endophilin-A, a protein at the heart of synaptic vesicle endocytosis and recycling, our findings provide a molecular link between recessive Parkinson's genes and defects in synaptic transmission.

    PhysOrg.com - latest science and technology news stories 2010

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