from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A vasoconstricting oligopeptide that plays a key role in vascular homeostasis.


Sorry, no etymologies found.


  • The three drugs block a chemical called endothelin that causes blood vessels to constrict. -- Top News

  • It is already proven that Walnuts have the ability to control the levels of endothelin, which is the primary cause for the inflammation of blood vessels. New Blogs and RSS Feeds

  • In their experiments on mice with scarring diseases, the researchers also found elevated levels of a protein called endothelin-1.

    India eNews

  • Investigators also found elevated levels of a protein called endothelin-1.

    Health News from Medical News Today

  • It is these polyphenols that are responsible for acting on blood vessels to suppress endothelin production and thus help prevent heart disease.

    Drinking to Good Health

  • And another study found that postmenopausal women with elevated testosterone had increases in markers of inflammation and endothelial dysfunction, C-reactive protein (CRP) and endothelin, that have been associated with increased risk of atherosclerosis.

    Doug Bremner: Wow! A Drug That Will Let Me Have Sex Once More a Month? Sign Me Up!

  • Macitentan is a highly potent, tissue-targeting endothelin receptor antagonist discovered in an in-house research program.

    Reuters: Press Release

  • Actelion's first drug Tracleer®, an orally available dual endothelin receptor antagonist, has been approved as a therapy for pulmonary arterial hypertension.

    Reuters: Press Release

  • In contrast to the tolerability profile of other endothelin receptor antagonists in previous clinical studies, there were no relevant findings of headache, hypotension, nasopharyngitis, rhinitis and hot flush.

    Reuters: Press Release

  • Through complete blockade of tissular endothelin, macitentan is expected to protect tissue from the damaging effect of elevated endothelin, specifically in the cardiovascular system.

    Reuters: Press Release


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