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- noun Plural form of
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Thus cyclic diynes of 8-10 member size as well as aza-enediynes have been shown to efficiently undergo Bergman cyclization under the induction of light, metal ions or elevated temperature due to their low activation barrier
Wright JM, Hynd G, Wyatt JK, Yancisin M, et al. (2000) Protein-degrading enediynes: library screening of Bergman cycloaromatization products.
So far several enediynes of both synthetic and fungal metabolite origins have been shown to display strong antitumor activity
USA: Marcel Dekker Inc. Fouad FS, Wright JM, Plourde G 2nd, Purohit AD, Wyatt JK, et al. (2005) Synthesis and protein degradation capacity of photoactivated enediynes.