Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A
drug used in the treatment ofParkinson's disease .
Etymologies
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Examples
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Orion expects the costs of the legal proceedings against the Sandoz companies to be substantially less than the costs of the entacapone patent litigation that had previously been pending in the United States.
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Orion's drugs for treatment of Parkinson's disease are Stalevo ® (active ingredients carbidopa, levodopa and entacapone) and Comtess ®/Comtan® (entacapone), and their net sales in January-June 2011 totalled EUR 143 (126) million.
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Orion expects the costs of the legal proceedings against Caraco to be substantially less than the costs of the entacapone patent litigation that had previously been pending in the United States.
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The Company is also conducting the ASCEND-PD comparative study of IPX066 and carbidopa-levodopa and entacapone, and an Open-Label Extension study for subjects from the ADVANCE-PD and APEX-PD studies is also ongoing.
unknown title 2011
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Results from the ASCEND-Parkinson's Disease (ASCEND -PD) study showed a 33.5% decrease in "off-time" in the IPX066 arm compared to a 10% decrease in the carbidopa-levodopa plus entacapone (CLE) arm.
unknown title 2011
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In June the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) issued a positive opinion recommending the granting of marketing authorisation for Orion's new entacapone and levodopa/carbidopa/entacapone products.
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Mylan intends to market in the United States a generic version of entacapone tablets with strength 200 mg like Orion's Comtan ® proprietary drug.
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The companies said that IPX066 demonstrated statistically significant improvement over carbidopa-levodopa plus entacapone in reducing the percentage of "off time" during waking hours.
unknown title 2011
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The addition of entacapone to carbidopa/levodopa has been shown to lead to a greater degree of improvement in some of the symptoms of Parkinson's disease than treatment with carbidopa/levodopa alone.
foodconsumer.org 2010
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Entacapone is also available as a single ingredient product (sold under the brand name Comtan) to be always administered in association with carbidopa/levodopa (entacapone has no antiparkinsonian effect of its own).
foodconsumer.org 2010
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