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epileptogenesis

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The process by which the brain develops epilepsy

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

epilepto- + -genesis

Examples

  • These may lead to status epilepticus (SE), a condition of persistent seizures, and evolve into chronic epilepsy after a latent period of epileptogenesis.

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  • A (1993) Axon terminal hyperexcitability associated with epileptogenesis in vitro.

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  • These findings fuelled a controversial debate on the role of astrocytes in focal epileptogenesis and in the generation of epileptiform discharges In the present study, we used different models of epileptic seizures, including a new model of focal seizures, to define the role of astrocytes in the generation of epileptiform activities.

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  • This hypothesis stems from a series of recent studies that reappraised the role of neurons in epileptogenesis and hinted at a possible, direct contribution of astrocytes to the generation of an epileptic discharge.

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  • Gastens AM, Sun M, Hausknecht M, Loscher W (2006) Treatment with valproate after status epilepticus: effect on neuronal damage, epileptogenesis, and behavioral alterations in rats.

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  • * Recent advances about the nature of alterations in ion channel structure or function which may be responsible for epileptogenesis

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  • We are interested in structure and plasticity of cortical circuits, and epileptogenesis following traumatic brain injury.

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  • These data suggest that, differently from the animal models, in human patient SE cannot be considered a sufficient condition for epileptogenesis.

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  • This report evidences the distinction and the different contribution in epileptogenesis of two processes, inflammation and neuronal death, that could not be consequent, but subsequent processes

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  • However, there is a wealth of data indicating that SE, with a minimal duration of 30-60 min is required for epileptogenesis consequently, SRS has mainly been considered as functional response of the abnormal neuronal circuitry subsequent to post-SE brain damage

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