Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics A
heritable change ingene expression that does not affect the actualbase pair sequence ofDNA .
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
From epi- + mutation; compare epigenetic.
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Examples
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"People are now beginning to realize that there are probably things that don't get wiped out or erased in the germ cells," he says, "so these are so-called epimutations that can be passed on from parents to children and to grandchildren — not genetic changes passed on, like Mendel, but an epimutation."
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Therefore, the ICR1 hypomethylation epimutation provides the strongest insight into the genetic cause of SRS and suggests that gene products involved in the establishment of DNA methylation at ICR1 may be mutated in SRS patients with hypomethylation.
PLoS ONE Alerts: New Articles Jeremiah Bernier-Latmani et al. 2009
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