from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
Sorry, no etymologies found.
"People are now beginning to realize that there are probably things that don't get wiped out or erased in the germ cells," he says, "so these are so-called epimutations that can be passed on from parents to children and to grandchildren — not genetic changes passed on, like Mendel, but an epimutation."
These modifications, called epimutations, can turn genes on and off, often at inappropriate times.
In the 1990s, meanwhile, scientists like Allis reported basic but breathtaking discoveries that showed how several groups of enzymes, common to every cell, could create epimutations without ever changing the DNA script.
CTCFL, which would provide a genetic link to the epimutations observed in these patients.
For the study of DNA methylation, plants provide an excellent model system, since they can tolerate major changes in their DNA methylation patterns and have long been studied for the effects of DNA methylation on transposons and epimutations.
(cancer of the colon, lung, breast and prostate), abnormal epigenetic modifications (i.e., epimutations) have been detected, such as the erroneous repression of genes by methylation of histone H3 on lysine 27.