epithelialisation love



from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of epithelialization.


Sorry, no etymologies found.


  • The subcellular mechanisms of TGF-β1 are crucially important to understanding its functions in re-epithelialisation and effective research tools are needed due to the limitations of current biological models

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  • As well as the auto-regulation mechanism, the influence of the ECM matrix and of TGF-β1 on cell proliferation were simulated expilicitly, while the influence of other factors on cell proliferation were modelled implicitly in the re-epithelialisation model.

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  • In the 3D model of the epidermis (which will also be referred to as the re-epithelialisation model in the second part of this paper), there are attractive and repelling forces between different agents as in the previous model.

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  • In normal human epidermis, relatively low levels of TGF-β1 are expressed predominantly in the suprabasal, differentiating layers, suggesting it may have a role in maintaining the cessation of growth in the differentiating cells of epidermis During re-epithelialisation, the expression of TGF-β1 is induced by various ECM components.

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  • The extensive in vitro and in vivo experimental literature describing its actions nevertheless describe an apparent paradox in that during re-epithelialisation it acts as proliferation inhibitor for keratinocytes.

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  • In this research, extensive literature of TGF-β1 synthesis, expression, secretion, activation, signalling and function during re-epithelialisation were analysed carefully.

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  • The agents 'rule set which now embed TGF-β1 functions and the biochemical equations used in COPASI were based on the analysis of qualitative or semi-quantitative biological data about TGF-β1 synthesis, expression, activation, signaling and biological functions during re-epithelialisation.

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