Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry An enzyme that produces hydroxyeicosatetraenoic acids (HETEs) and epoxyeicosatrienoic acids (EETs) from arachidonic acid, causing effects such as cell proliferation and decrease in cyclooxygenase activity.

Etymologies

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Examples

  • Our findings indicate that a neuronal P450 epoxygenase mediates the pain-relieving properties of morphine.

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  • Figure 3: Effects of P450 and epoxygenase inhibitors on morphine antinociception.

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  • The eicosanoids: cyclooxygenase, lipoxygenase, and epoxygenase pathways

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  • Recommended name unspecific monooxygenase Synonyms 3AH15 6 b-hydroxylase 6-b-testosterone hydroxylase aldehyde oxygenase arachidonic acid epoxygenase brain aromatase CYP102

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  • Alkene monooxygenase 1.14.13.69 1 Nomenclature EC number 1.14.13.69 Systematic name alkene, NADH: oxygen oxidoreductase Recommended name alkene monooxygenase Synonyms AMO alkene epoxygenase propene monooxygenase CAS registry number 63439-50-9 2 Source Organism

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  • Tomer KB, Falck JR, Zeldin DC (1996) Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart.

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  • Ruan X, Yang B, Spiecker M, et al. (1999) Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.

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  • Here we show CYP2J2 can act as an endogenous epoxygenase source of high affinity PPAR ligands.

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  • Cells were co-transfected with PPAR reporter gene, CYP2J2 and PPARα, and treated with the epoxygenase inhibitor SKF525A (0-30 µM).

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