from Wiktionary, Creative Commons Attribution/Share-Alike License
- adj. Of or pertaining to euchromatin
Sorry, no etymologies found.
However, upon β-catenin stabilization, it associates with β-catenin inside the euchromatic nuclear compartment, and its binding to target DNA is enhanced along with recruitment of β-catenin and H3K9 acetylation.
The major force driving the degeneration of Y chromosomes are retrotransposons in remodelling former euchromatic chromosome structures into heterochromatic ones.
Our molecular maps demonstrate that heterochromatin can invade a normally euchromatic region, yet the strength of HP1 binding and effects on gene expression are highly dependent on local context.
These findings suggest that DNA demethylating interventions alone are not able to restore a complete euchromatic status and a full transcriptional reactivation of the epigenetically silenced tumor suppressor genes, and reinforce the necessity of targeting multiple elements of the epigenetics machinery for a successful treatment of malignancies.
Knock-down and transfection experiments for DOT1L show that this enzyme has a direct role in maintaining the euchromatic and active status of these genes when unmethylated.
Segmental duplications (SDs) are euchromatic portions of genomic DNA ([greater than or equal to] 1kb) that occur at more than one site within the genome, and typically share a high level of sequence identity (>