extragenic

The 3′ and 5′ ends of the genome contain short extragenic sequences known as the 'leader' and

PLoS ONE Alerts: New Articles Arthur S. Samuel et al. 2010

For example, it is now known that the underlying cause of cancer is “chromosomal instability,” or damage to extragenic structures - not mutations to individual genes.

Long weekend fix of stories in the ID controversy: Denyse O 2005

Pol_II peaks are extremely broad, covering about 20 kb of extragenic sequence with no annotation of known or predicted exons; moreover their height is much lower than that found inside the coding region.

PLoS Biology: New Articles Francesca De Santa et al. 2010

One model supported by experimental data is that extragenic transcription leads to the repeated passage of several

PLoS Biology: New Articles Francesca De Santa et al. 2010

Moreover, much of this extragenic transcription is regulated by stimulation.

PLoS Biology: New Articles Francesca De Santa et al. 2010

We therefore searched our dataset of 2,236 predicted enhancers associated with extragenic Pol_II for enriched TFBSs.

PLoS Biology: New Articles Francesca De Santa et al. 2010

Moreover, extragenic transcription was downregulated when the coding gene reached its maximal level of expression, a result particularly obvious at Cxcl11.

PLoS Biology: New Articles Francesca De Santa et al. 2010

A curated dataset of extragenic Pol_II peaks in mouse macrophages.

PLoS Biology: New Articles Francesca De Santa et al. 2010

We thus applied this machine-learning algorithm to the dataset of 4,588 extragenic Pol_II peaks described above.

PLoS Biology: New Articles Francesca De Santa et al. 2010

A second expected feature of a ripple effect is that extragenic waves of Pol_II should show continuity with Pol_II elongating from the inducible coding gene.

PLoS Biology: New Articles Francesca De Santa et al. 2010