from The American Heritage® Dictionary of the English Language, 4th Edition
- adj. Located or occurring outside a blood or lymph vessel.
- adj. Lacking vessels; nonvascular.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- adj. Situated or happening outside of the blood vessels or lymph vessels
from the GNU version of the Collaborative International Dictionary of English
- adj. Outside the vessels; -- said of the substance of all the tissues.
- adj. Destitute of vessels; non-vascular.
from The Century Dictionary and Cyclopedia
- Being out of the proper vessel or vessels; without distinct vessels: applied especially to the free circulation of the blood of insects between the viscera and the muscles, without special veins or arteries.
- Nonvascular: applied to parts which have no blood-vessels: as, cuticle and cartilage are extravascular structures.
Sorry, no etymologies found.
So, some kind of trauma has to happen which allows blood to escape from a blood vessel into what's called the extravascular space.
I believe the intrinsic coagulation system initiated by the contact system would be more important as a host defense system working extravascular tissue space against microbial pathogens than as the haemostatic mechanism.
By means of these ameboid properties the cells have the power of wandering or emigrating from the bloodvessels by penetrating their walls and thus finding their way into the extravascular spaces.
Batten SJ (1984) Genesis of B lymphocytes in the bone marrow: extravascular and intravascular localization of surface IgM-bearing cells in mouse bone marrow detected by electron-microscope radioautography after in vivo perfusion of 125I anti-IgM antibody.
Distribution volume is approximately equal to or slightly larger than serum volume suggesting minimal extravascular distribution.
The beta agonist lung injury trial (BALTI) has shown that treatment with intravenous albutamol (15ug/kg/hr) reduces extravascular lung water (EVLW) in patients with ALI/ARDS with a reduction in plateau pressures at Day 7.
Proleukin administration has been associated with capillary leak syndrome (CLS) which is characterized by a loss of vascular tone and extravasation of plasma proteins and fluid into the extravascular space.
But after a crushing injury-or any condition that depletes protein stores like liver failure or malnutrition-the fluid becomes sequestered in an extravascular space.
After 1 L of 5\% albumin has been infused, plasma volume expansion ranges from 500 to 1000 mL. 52, 53 Mobilization of extravascular volume is required for effective increases in intravascular volume when using
Experimental reports in septic models demonstrate no increase in extravascular lung water when hydrostatic pressures are maintained at low levels, indicating that in sepsis, the primary determinant of extravascular fluid flux appears to be microvascular pressure rather than colloid osmotic pressure. 65 Taken together, these data suggest that when lower filling pressures are maintained, there is no significant difference in the development of pulmonary edema with crystalloids or colloids.