from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A urate-lowering drug, an inhibitor of xanthine oxidase that is indicated for use in the treatment of hyperuricemia and chronic gout.


Sorry, no etymologies found.


  • "Similar reductions in serum urate produced when RD.A594 and febuxostat were administered alone, and the substantial reduction produced when these agents were administered in combination supports our strategy to develop RD.A594 as both monotherapy and in combination with xanthine oxidase inhibitors, such as febuxostat or allopurinol," added Barry D. Quart,


  • A Phase 3 study of lesinurad in combination with febuxostat is also planned.

  • Lesinurad has been evaluated as a single agent and in combination with the approved xanthine oxidase inhibitors, allopurinol and febuxostat.

  • In addition, because increasing the excretion of uric acid is additive to the effects of drugs known as xanthine oxidase inhibitors that decrease the production of uric acid, including allopurinol and febuxostat, lesinurad in combination with such drugs has the potential to treat the significant portion of the gout population that is not adequately treated with existing therapies.

  • Furthermore, Ardea also intends to study lesinurad in conjunction with Takeda's gout therapy Uloric febuxostat in another late-stage trial.

  • This study will evaluate the cardiovascular safety of febuxostat compared to allopurinol in people who have both gout and cardiovascular problems.

    Yahoo! News: Business - Opinion

  • Positive results from Ardea Biosciences 'ongoing drug-drug interaction study of RDEA594 and febuxostat


  • The preventative drug, allopurinol, can only be administered when the condition has calmed down, and has to be taken for the rest of your life as does the newly approved medication, febuxostat.

    Life and style |

  • This phase 3b study will evaluate the cardiovascular safety of febuxostat and allopurinol in people with gout and cardiovascular problems.

    Yahoo! News: Business - Opinion

  • Besides a low purine diet, preventive medicines such as allopurinol, febuxostat, and probenecid can be used to prevent recurrences.

    The Daily Times News Headlines


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