Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of a class of proteins that bind actin filaments and anchor membrane proteins

Etymologies

Sorry, no etymologies found.

Examples

  • Johansen L, Naumanen T, Knudsen A, Westerlund N, Gromova I, et al. (2008) IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.

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  • This protective effect is mediated via a high-affinity interaction of NLX to a pentapeptide region in c-terminal filamin A (FLNA), a scaffolding protein interacting with MOR.

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  • Frankfurt M, Burns LH (2008) High-affinity naloxone binding to filamin A prevents mu opioid receptor-Gs coupling underlying opioid tolerance and dependence.

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  • Feng Y, Walsh C (2004) The many faces of filamin: A versatile molecular scaffold for cell motility and signalling.

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  • Incidentally, on questions of biochem and molbiol what's your view on the role of filamin A as an endocrine effector?

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