Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any of a class of
proteins that bindactin filaments and anchor membrane proteins
Etymologies
Sorry, no etymologies found.
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Examples
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Johansen L, Naumanen T, Knudsen A, Westerlund N, Gromova I, et al. (2008) IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.
PLoS ONE Alerts: New Articles Moran Valensi-Kurtz et al. 2010
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This protective effect is mediated via a high-affinity interaction of NLX to a pentapeptide region in c-terminal filamin A (FLNA), a scaffolding protein interacting with MOR.
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Frankfurt M, Burns LH (2008) High-affinity naloxone binding to filamin A prevents mu opioid receptor-Gs coupling underlying opioid tolerance and dependence.
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Feng Y, Walsh C (2004) The many faces of filamin: A versatile molecular scaffold for cell motility and signalling.
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Incidentally, on questions of biochem and molbiol what's your view on the role of filamin A as an endocrine effector?
RealClimate 2009
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