from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Any of a class of proteins that bind actin filaments and anchor membrane proteins
Sorry, no etymologies found.
Johansen L, Naumanen T, Knudsen A, Westerlund N, Gromova I, et al. (2008) IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.
This protective effect is mediated via a high-affinity interaction of NLX to a pentapeptide region in c-terminal filamin A (FLNA), a scaffolding protein interacting with MOR.
Frankfurt M, Burns LH (2008) High-affinity naloxone binding to filamin A prevents mu opioid receptor-Gs coupling underlying opioid tolerance and dependence.
Feng Y, Walsh C (2004) The many faces of filamin: A versatile molecular scaffold for cell motility and signalling.
Incidentally, on questions of biochem and molbiol what's your view on the role of filamin A as an endocrine effector?