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  • However, WestLB analyst Norbert Barth believes Bristol-Myer Squibb's Co. and Pfizer Inc.'s Eliquis has the potential to become the first-line treatment option for the atrial fibrillation indication, whereas Xarelto might be used in more advanced stages, limiting the product's overall peak sales potential.

    Bayer Rises on U.S. Approval for Blood Thinner

  • The Drugs for Neglected Diseases Initiative says the goal is to develop a first-line therapy for children that is effective, available and affordable.

    New Initiative Provides Better Treatment for Pediatric AIDS

  • Bristol said a separate study is testing brivanib as a potential first-line treatment in newly diagnosed liver-cancer patients.

    Bristol-Myers Drug Misses Survival Goal in Liver-Cancer Trial

  • "We have not yet reflected the use of the drug in liver, gastric and first-line breast cancer, with results expected during 2012 to 2104, which, if positive, could double our current forecast," he said.

    Novartis Tumor Pill Wins European Approval

  • The company said it continues to expect a decision from European regulators in the first half of this year on using Revlimid as a first-line treatment for the blood cancer multiple myeloma.

    Celgene to Acquire Biotech Firm Avila

  • The EMA panel, whose opinions are usually followed by the European Commission, said it is recommending that Avastin in combination with chemotherapy Xeloda should be extended to include first-line treatment of patients with metastatic-breast cancer in whom treatment with other chemotherapy options isn't considered appropriate.

    Roche's Avastin Drug Gets Boost in Europe

  • GM Brian Burke said April 28 that there were "no developments" with restricted free agent RW Nikolai Kulemin, who saw some first-line duty in 2009-10. —

    Toronto Maple Leafs Team Report

  • Regulators have become wary of PFS, especially for first-line treatments.

    Roche to File Cancer Drug

  • Over the next five to six years, these new clinical trials will evaluate treatment alternatives for diseases for which antibiotics are prescribed most often, including acute otitis media (middle ear infections), community-acquired pneumonia and diseases caused by Gram-negative bacteria, which frequently are resistant to first-line antibiotics.

    Antimicrobial Resistance: 8 Large NIH Trials Seek To Preserve The Usefulness Of Antibiotics

  • Additionally, there has been a change in the medical community's thinking around the use of IUDs; in the past, these long-acting methods were often only recommended for women who had already had children, but there is no medical justification for this limitation, and the method is now seen as a "first-line" option for teens who are sexually active and want to delay childbearing for several years.

    Sharon L. Camp: Behind the Sharp Decline in Teen Births


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