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Examples
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Such forward-looking statements include statements concerning the potential for pralatrexate to demonstrate anticancer activity in solid tumors, the potential correlation between the sensitivity to pralatrexate and the expression level of folyl-polyglutamate synthetase, and other statements which are other than statements of historical facts.
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Further analysis of the data demonstrated a potential correlation between the sensitivity to pralatrexate and the expression level of folyl-polyglutamate synthetase (FPGS), an enzyme that catalyzes the addition of polyglutamate tails to folate derivatives such as pralatrexate.
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The presentation also demonstrated a rapid anti-cancer effect for the drug (within 24-72 hours) and the identification of a potential enzyme biomarker (folyl-polyglutamate synthetase or FPGS) to predict which patients will benefit from treatment with the drug.
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