from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. An antiviral drug, CNa3O5P, used in the treatment of several AIDS-related infections including cytomegalovirus retinitis.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A phosphonic acid derivative used as an antiviral drug to treat herpes viruses.


from The American Heritage® Dictionary of the English Language, 4th Edition

Alteration of phos(phorus) + car(bon) + net (probably shortening and alteration of Latin natrium, sodium; see natron).


  • The FDA is also allowing imports from Britain of foscarnet, an antibiotic sometimes used after organ transplants.

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  • AiCuris says that AIC246 also demonstrated efficacy in the treatment of one patient who had developed viremia due to HCMV that was resistant to ganciclovir, foscarnet, and cidofovir.

    GEN News Highlights

  • Despite therapy with a combination of antiviral drugs (ganciclovir, foscarnet and cidofovir), mortality is high (10 of 11 cases).

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  • The development of CMV CNS disease is associated with risk factors (T-cell depletion, anti-thymocyte globulin, umbilical cord blood transplantation) that cause severe and protracted T-cell immunodeficiency (8 of 11 cases), a history of recurrent CMV viremia treated with multiple courses of preemptive ganciclovir or foscarnet therapy (11 of 11 cases), and ganciclovir-resistant CMV infection (11 of 11 cases).

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  • An international panel that developed guidelines for treatment of CMV diseases in adults with AIDS receiving highly active antiretroviral therapy [73] recommended treatment with intravenous ganciclovir, intravenous foscarnet, or a combination of the two drugs.

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  • Patients who develop CMV polyradiculopathy while on ganciclovir or foscarnet therapy should receive combination therapy with both drugs.

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  • Ganciclovir and foscarnet have been used, but their efficacy is unknown.

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