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frameshift mutation

Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A mutation in a DNA chain that occurs when the number of nucleotides inserted or deleted is not a multiple of three, so that every codon beyond the point of insertion or deletion is read incorrectly during translation.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. a genetic mutation that either inserts or deletes a series of nucleotides that is not divisible by three and thus disrupts gene expression by codons

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