frameshifts

I assume that when we say mutation, the consensus definition is not simply single nucleotide alterations or frameshifts.

The Faith That Dare Not Speak Its Name - The Panda's Thumb 2005

Once the researchers suspected the MLL2 gene, follow-up sequencing using the traditional and highly accurate Sanger DNA sequencing method, more capable of reliably detecting frameshifts, was used to identify additional MLL2 loss-of-function gene variants, which lead to a loss of function in two of the three remaining cases.

innovations-report 2010

This results in translational frameshifts that access alternative open reading frames downstream, generating the V and W/I proteins.

PLoS ONE Alerts: New Articles Arthur S. Samuel et al. 2010

Most of these mutations were expressed as frameshifts or splicing errors and resulted in no or very little IL2RG mRNA being expressed as shown in Injection of Il2rg ZFN-encoding mRNA into rat embryos induced targeted loss-of-function mutations.

PLoS ONE Alerts: New Articles Tomoji Mashimo et al. 2010

They may be used to produce frameshifts or small in-frame deletions such as the 3-bp deletion that we observed.

PLoS ONE Alerts: New Articles Tomoji Mashimo et al. 2010

A variety of pseudogene annotations from multiple sources were pooled and filtered to obtain a subset of sequences that have significant mid-sequence disablements (frameshifts and premature stop codons), and that have clear evidence of full-length mRNA transcription.

BioMed Central - Latest articles Amit Khachane 2009

We’re aware of no mechanism that could be targeting these frameshifts in any way.

What is Science? « UDreamOfJanie 2006