Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun Any of a group of galactose-containing cerebrosides found in the surface membranes of nerve cells.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any of several
galactocerebrosides found in the surfacemembranes ofnerve cells .
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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Tay-Sachs is a fatal condition in which harmful amounts of liquid fatty substances called ganglioside GM2 are built up in tissue and nerve cells.
Signs of the Times 2009
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The study suggests that the substance, Gm1 ganglioside, may stabilize injured neurons and may stimulate production of dopamine, the substance lacking in patients with Parkinson's.
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It also significantly reduced bacterial adherence to and invasion of HEp-2 cells, and affected production of cholera toxin and binding of both E coli heat labile toxin and cholera toxin to ganglioside monosialic acid receptor.
foodconsumer.org 2010
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NgHexA was more efficiently taken up than the wild-type HexA and delivered to lysosomes, where it degraded accumulated substrates including GM2 ganglioside (GM2) when administered to cultured fibroblasts derived from a Sandhoff disease (SD) patient.
Naturejobs - All Jobs Kazuhiko Matsuoka 2010
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Brijesh and colleagues tested the preparation for its antibacterial, antigiardial and antiviral activities including its effect on adherence of enteropathogenic Escherichia coli, invasion of enteroinvasive E. coli, Shigella flexneri to HEp-2 cells; production of E. coli heat labile toxin, cholera toxin, and their binding to ganglioside monosialic acid receptor; and production and action of E. coli heat stable toxin.
foodconsumer.org 2010
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The production of E. coli heat labile toxin (LT) and cholera toxin (CT) and their binding to ganglioside monosialic acid (GM1) were studied by GM1-ELISA whereas the production and action of E. coli heat stable toxin (ST) was assessed by suckling mouse assay.
BioMed Central - Latest articles Tannaz Birdi 2010
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The vaccine is intended to instruct the patient's immune system to make antibodies against the three ganglioside antigens present on the surface of sarcoma cells.
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Pre-clinical pharmacology studies suggest that MORAb-028 binds to GD2, a cell surface ganglioside that is expressed on cells associated with carcinoma and a subset of other cancer types.
THE MEDICAL NEWS 2010
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The vaccine is a trivalent ganglioside vaccine administered with an immunological adjuvant in a series of 10 subcutaneous injections given over an 84-week period.
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To discover the mechanism that drives ganglioside-mediated protection from a-synuclein-caused cell death, Wei et al treated cells with a molecule that disrupts the function of lysosomes, cell components responsible for digesting unneeded and excess material in cells.
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