from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of several proteolytic enzymes that catalyze the hydrolysis of gelatine

from The Century Dictionary and Cyclopedia

  • n. A ferment which liquefies gelatin but which does not digest coagulated egg-albumin or fibrin in either acid, neutral, or alkaline solutions.


Sorry, no etymologies found.


  • A novel diagnostic test to rapidly detect neutrophil gelatinase-associated lipocalin


  • Morrison CJ, Butler GS, Bigg HF, Roberts CR, Soloway PD, et al. (2001) Cellular activation of MMP-2 (gelatinase A) by MT2-MMP occurs via a TIMP-2-independent pathway.

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  • This compares favorably with other established biomarkers of AKI such as kidney injury molecule-1, neutrophil gelatinase-associated lipocalin,

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  • These cells showed reduced migration and invasion that paralleled decreased gelatinase MMP-2 activity and increased expression and secretion of tissue inhibitor of metalloproteinase-1 (TIMP-1) and TIMP-2.

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  • The gelatinases comprise MMP-2 (gelatinase A) and MMP-9 (gelatinase B), both of which cleave several components of the extracellular matrix.

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  • To identify factors that might predict response to sunitinib in patients with renal cell carcinoma, we measured serum vascular endothelial growth factor (VEGF) and neutrophil gelatinase-associated lipocalin (NGAL) levels.

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  • The FDA has accepted for review a diagnostic test from Abbott Laboratories which can detect neutrophil gelatinase-associated lipocalin (NGAL), a biomarker which indicates that a patient is at risk for acute kidney injury (AKI).


  • Collagenase-1, stromelysin-1 and 92 kDa gelatinase are associated with tumor necrosis factor-alpha induced morphological change of human endothelial cells in vitro.

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  • TNF-alpha and IL-1beta selectively induce expression of 92-kDa gelatinase by human macrophages.

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  • Leppert D, Waubant E, Burk MR, Oksenberg JR, Hauser SL (1996) Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis.

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