germ-line

If the cells of the immune system can use well-defined natural genetic engineering processes to make change when change is needed, there is a scientific basis for saying that germ-line cells might do the same in the course of evolution.

James A. Shapiro: Purposeful, Targeted Genetic Engineering in Immune System Evolution James A. Shapiro 2012

If the cells of the immune system can use well-defined natural genetic engineering processes to make change when change is needed, there is a scientific basis for saying that germ-line cells might do the same in the course of evolution.

James A. Shapiro: Purposeful, Targeted Genetic Engineering in Immune System Evolution James A. Shapiro 2012

But changes wrought by so-called germ-line therapy alter the blueprint itself, the human genome, and would thus be passed on to offspring.

Building Humans – ‘Unnatural’ Selection | Impact Lab 2009

Robertson, E. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines.

The 2007 Nobel Prize in Physiology or Medicine - Advanced Information 2007

The pattern can be explained by assuming that spontaneous germ-line mutation is a significant cause of the disorder.

July 24th, 2007 2007

Why should society treat my donation any differently simply because it contains a germ-line cell rather than somatic tissue?

Jacob M. Appel: Revenge of the Sperm Donors 2009

Bioethicists who support germ-line GM counter these arguments with others: parents have reproductive autonomy (Zimmerman 1991); the fetus is being treated as a patient in prenatal surgeries, so why not the embryo (Nolan 1991); we constantly modify the conditions future generations inherit, and usually not with altruistic purposes (e.g., degraded environments) (Peters 1995); members of future generations would presumably consent to an augmentation of Rawlsian primary goods

The Human Genome Project Gannett, Lisa 2008

Some bioethicists argue that the distinction between somatic cell and germ-line GM has moral significance, and that somatic cell interventions alone are permissible.

The Human Genome Project Gannett, Lisa 2008

In Dawkins 'terminology, the genes that code for our immune system are active, germ-line replicators.

Replication Hull, David 2008

Of the four classes of interventions delineated by somatic-cell/germ-line and therapy/enhancement distinctions, only germ-line GM for enhancement purposes remains particularly contentious among bioethicists (Allhoff 2005).

The Human Genome Project Gannett, Lisa 2008