from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any
enzymethat catalyzes the conversion of glutamineto glutamic acidand ammonia
from Wiktionary, Creative Commons Attribution/Share-Alike License
One of the proteins that responded to the Myc gene, glutaminase (GLS), supports the production of cellular energy.
A glutamine amidotransferase consisting of the synthase Pdx1 and its glutaminase partner, Pdx2, form a complex that directly synthesizes PLP from ribose 5-phosphate, glyceraldehyde 3-phosphate, and glutamine.
The multiple catalytic ability of Pdx1, the remote glutaminase and synthase active sites, and the elaborate structure suggest regulation of activity on several levels.
12 Pdx2 subunits attach, with the glutaminase and synthase active sites remote from each other.