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- noun organic chemistry The univalent
radicalderived from glutamine.
Sorry, no etymologies found.
Because glutaminyl-tRNA synthetase does not possess a spatially separate editing domain, these data demonstrate that a pre-transfer editing-like reaction can occur within the synthetic site of a class I tRNA synthetase.
This hydrolysis of glutaminyl adenylate represents a novel reaction that is directly analogous to the pre-transfer editing hydrolysis of noncognate aminoacyl adenylates by editing synthetases such as isoleucyl-tRNA synthetase.
A similar mechanism can be suggested for FLG2 repeats to aggregate lysine-rich proteins because these repeats almost lack cysteine or lysine residues but contain high glutamine contents, implicating that they may act as amino acceptors in transglutaminase-catalyzed reactions to generate glutaminyl-lysine cross-links with neighbouring proteins
They concentrated their attention on the enzyme glutaminyl cyclase (QC), found in higher quantities in the brains of Alzheimer's patients.
1999 Gene descent, duplication, and horizontal transfer in the evolution of glutamyl- and glutaminyl-tRNA synthetases.