glycosphingolipid love

glycosphingolipid

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. a lipid that contains at least one monosaccharide unit and either a sphingoid or a ceramide

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

glyco- +‎ sphingolipid

Examples

  • Investigators reported that in healthy cells these regions, known as glycosphingolipid-enriched microdomains, or GEMs, include tiny amounts of GM1.

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  • Chakrabandhu K, Huault S, Garmy N, Fantini J, Stebe E, et al. (2008) The extracellular glycosphingolipid-binding motif of Fas defines its internalization route, mode and outcome of signals upon activation by ligand.

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  • We noticed differences in the response of given cells that we interpret to be due to the existence of cells that poorly bind Stx, probably because of differences in the expression level of the Stx glycosphingolipid receptor Gb3.

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  • The present work deals with the trafficking of glycosphingolipid GD3 to the mitochondrion upon pro-apoptotic triggering induced by CD95/Fas ligation and identifies the pivotal role of microtubule-associated protein CLIPR-59 in instructing and regulating GD3-microtubule association.

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  • Microtubules may be used as tracks to direct intracytoplasmic transport of lipid raft glycosphingolipid (s) to mitochondria.

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  • To assess the role of glycosphingolipid recognition by F18-fimbriated

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  • The only glycosphingolipid with F18-binding activity of the blood group O pig was an H type 1 pentaglycosylceramide

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  • In contrast, CD failed to ameliorate cholesterol or glycosphingolipid storage in GM1 gangliosidosis and MPS IIIA disease.

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  • Lachmann RH, Platt FM (2001) Substrate reduction therapy for glycosphingolipid storage disorders.

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  • Gehrmann M, Liebisch G, Schmitz G, Anderson R, Steinem C, et al. (2008) Tumor-specific Hsp70 plasma membrane localization is enabled by the glycosphingolipid Gb3.

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