Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry Any enzyme that splits a glycoside into a glycone and aglycone

Etymologies

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Examples

  • The DNA glycosylase is used to break the β-N glycosidic bond to create an AP site.

    Another Protozoan and Front-Loading 2006

  • Since it was first identified about eight years ago, NEIL3 has been believed to be a basic DNA-maintenance enzyme of a type called a glycosylase.

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 2010

  • Analysis of these bodily fluids showed a 20 percent reduction in DNA damage, measured using the formamidopyrimidine glycosylase (Fpg) enzyme-assisted comet assay.

    NutraIngredients RSS 2010

  • Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, et al. (2008) DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

    PLoS ONE Alerts: New Articles Mehregan Movassagh et al. 2010

  • Benecke A, Um SJ, Torchia J, Evans RM, et al. (2002) Association of CBP / p300 acetylase and thymine DNA glycosylase links DNA repair and transcription.

    PLoS ONE Alerts: New Articles 2009

  • Human 8-oxoguanine DNA glycosylase 1 (hOGG1) has a major role in the repair of 8-hydroxyguanine, a major promutagenic DNA lesion.

    Naturejobs - All Jobs Toshiki Okasaka 2009

  • Pta 11528 encodes two glycosyl transferases (C1E_0355 and C1E_0361) and a thermostable glycosylase (C1E_4802) that do not have homologues in any of the three fully sequenced

    BioMed Central - Latest articles 2009

  • Endonuclease VIII (Nei) is a DNA glycosylase of the base excision repair pathway that recognizes and excises oxidized pyrimidines.

    Journal of Biological Chemistry current issue Imamura, K., Wallace, S. S., Doublie, S. 2009

  • a system with purified HSV-1 and human proteins that perform all the steps of uracil DNA glycosylase-initiated base excision repair.

    Journal of Biological Chemistry current issue Bogani, F., Chua, C. N., Boehmer, P. E. 2009

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