Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Either of a pair of related thiol-dependent enzymes: glyoxalase І, which catalyses the isomerisation of the spontaneously formed hemithioacetal adduct between GSH and 2-oxoaldehydes (such as methylglyoxal) into S-2-hydroxyacylglutathione; and glyoxalase ІІ, which hydrolyses these thiolesters.

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

glyoxal +‎ -ase

Examples

  • It was perhaps for this reason that the next enzyme, of the sequence, glyoxalase

    Irwin Rose - Autobiography

  • The detoxification of reactive ketoaldehydes such as methylglyoxal (MG) by glyoxalase I and II protects cells from formation of advanced glycation end products (AGEs).

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  • Landgraf R, Kessler MS, Bunck M, Murgatroyd C, Spengler D, et al. (2007) Candidate genes of anxiety-related behavior in HAB / LAB rats and mice: focus on vasopressin and glyoxalase-I.

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  • Kessler MS, Milfay D, Birg IN, Bunck M, et al. (2005) Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety.

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